Investigación & Desarrollo


Publicaciones relevantes

Plant-Based Nutrition: Exploring Health Benefits for Atherosclerosis, Chronic Diseases, and Metabolic Syndrome—A Comprehensive Review

Humberto Peña-Jorquera 1, Valeska Cid-Jofré 2 , Leslie Landaeta-Díaz 3,4 , Fanny Petermann-Rocha 5,6 , Miquel Martorell 7 , Hermann Zbinden-Foncea 8,9 , Gerson Ferrari 10,11, Carlos Jorquera-Aguilera 12 and Carlos Cristi-Montero

Toll like receptor expression induced by exercise in obesity and metabolic syndrome: A systematic review. Rada I, Deldicque L, Francaux M, Zbinden-Foncea H. Exerc Immunol Rev. 2018;24:60-71.

Generation of desminopathy in rats using CRISPR-Cas9 Henning T. Langer*,, Agata A. Mossakowski*, Leslie A. Stewart, Brandon J. Willis, Diana L. Young, Nichole L. Anchell, Kayla M. Jager, Phuong T. Dao, Kristin N. Grimsrud, Joshua A. Wood, Kent C. Lloyd, Hermann Zbinden-Foncea, and Keith Baar. Journal of Cachexia, Sarcopenia and Muscle. 2020

Does High Cardiorespiratory Fitness Confer Some Protection Against Proinflammatory Responses After Infection by SARS-CoV-2? Zbinden-Foncea H, Francaux M, Deldicque L, Hawley JA. Obesity. 2020

Acute and Chronic Effects of High Frequency Electric Pulse Stimulation on the Akt/mTOR
Pathway in Human Primary Myotubes. Valero-Breton M, Warnier G, Castro-Sepulveda M,
Deldicque L, Zbinden-Foncea H. | Frontiers in Bioengineering and Biotechnology 2020

Low abundance of Mfn2 protein correlates with reduced mitochondria‐SR juxtaposition and mitochondrial cristae density in human men skeletal muscle: Examining organelle measurements from TEM images. Castro‐Sepulveda M, Fernández‐Verdejo R, Tuñón‐Suárez M, Morales‐Zúñiga J, Troncoso M, Jannas‐Vela S, Zbinden‐Foncea H.   | The FASEB Journal. 2021

The fasting-feeding metabolic transition regulates mitochondrial dynamics. Castro- Sepúlveda M, Morio B, Tuñón-Suárez M, Jannas-Vela S, Díaz-Castro F, Rieusset J, Zbinden-Foncea H. | FASEB Journal. 2021

Lista de Publicaciones

  • Deldicque, L., Décombaz, J., Zbinden Foncea, H., Vuichoud, J., Poortmans, J. R., & Francaux, M. (2008). Kinetics of creatine ingested as a food ingredient. European journal of applied physiology, 102(2), 133-143.
  • Zbinden-Foncea, H., Raymackers, J. M., Deldicque, L., Renard, P., & Francaux, M. (2012). TLR2 and TLR4 activate p38 MAPK and JNK during endurance exercise in skeletal muscle. Medicine and science in sports and exercise, 44(8), 1463-1472.
  • Zbinden‐Foncea, H., Deldicque, L., Pierre, N., Francaux, M., & Raymackers, J. M. (2012). TLR2 and TLR4 activation induces p38 MAPK‐dependent phosphorylation of S6 kinase 1 in C2C12 myotubes. Cell biology international, 36(12), 1107-1113.
  • Zbinden-Foncea, H., Van Loon, L. J., Raymackers, J. M., Francaux, M., & Deldicque, L. (2013). Contribution of nonesterified fatty acids to mitogen-activated protein kinase activation in human skeletal muscle during endurance exercise. International journal of sport nutrition and exercise metabolism, 23(3), 201-209.
  • Zbinden-Foncea, H., Valenzuela, T., Espildora, F., Peñailillo, L., & Willems, P. A. (2014). Muscular power as a function of load in elderly women. Comput Methods Biomech Biomed Engin, 17(1), 92-93.
  • Méndez-Rebolledo, G., Guzmán-Muñoz, E., Gatica-Rojas, V., & Zbinden-Foncea, H. (2015). Longer reaction time of the fibularis longus muscle and reduced postural control in basketball players with functional ankle instability: A pilot study. Physical Therapy in Sport, 16(3), 242-247.
  • Castro-Sepúlveda, M., Cerda-Kohler, H., Pérez-Luco, C., Monsalves, M., Andrade, D. C., Zbinden-Foncea, H., … & Ramírez-Campillo, R. (2015). Hydration status after exercise affect resting metabolic rate and heart rate variability. Nutricion Hospitalaria, 31(3), 1273-1277.
  • Peñailillo, L., Maya, L., Niño, G., Torres, H., & Zbinden-Foncea, H. (2015). Salivary hormones and IgA in relation to physical performance in football. Journal of sports sciences, 33(20), 2080-2087.
  • Castro-Sepúlveda, M., Astudillo, S., Álvarez, C., Zapata-Lamana, R., Zbinden-Foncea, H., Ramírez-Campillo, R., & Jorquera, C. (2015). Prevalencia de deshidratación en futbolistas profesionales chilenos antes del entrenamiento. Nutrición hospitalaria, 32(1), 308-311.
  • Peñailillo, L., Espíldora, F., Jannas-Vela, S., Mujika, I., & Zbinden-Foncea, H. (2016). Muscle strength and speed performance in youth soccer players. Journal of human kinetics, 50(1), 203-210.
  • Maya, J., Marquez, P., Peñailillo, L., Contreras-Ferrat, A., Deldicque, L., & Zbinden-Foncea, H. (2016). Salivary biomarker responses to two final matches in women’s professional football. Journal of sports science & medicine, 15(2), 365.
  • Castro-Sepulveda, M., Cerda-Kohler, H., Pérez-Luco, C., Monsalves, M., Zbinden-Foncea, H., … & Ramírez-Campillo, R. (2016). Effects of beer, non-alcoholic beer and water consumption before exercise on fluid and electrolyte homeostasis in athletes. Nutrients, 8(6), 345.
  • Castro-Sepulveda, M., Astudillo, J., Letelier, P., & Zbinden-Foncea, H. (2016). Prevalence of dehydration before training sessions, friendly and official matches in elite female soccer players. Journal of human kinetics, 50(1), 79-84.
  • Peñailillo, L., Guzmán, N., Cangas, J., Reyes, A., & Zbinden-Foncea, H. (2017). Metabolic demand and muscle damage induced by eccentric cycling of knee extensor and flexor muscles. European Journal of Sport Science, 17(2), 179-187.
  • Peñailillo Escarate, L., Mackay Phillips, K., Serrano Duarte, N., Canales Espinoza, P., Miranda Herrera, P., & Zbinden-Foncea, H. (2016). Efectos de la suplementación de omega-3 y entrenamiento de intervalos de alta intensidad en el rendimiento físico, presión arterial y composición corporal en individuos sedentarios con sobrepeso. Nutrición Hospitalaria, 33(4), 848-855.
  • Zbinden-Foncea, H., Rada, I., Gomez, J., Kokaly, M., Stellingwerff, T., Deldicque, L., & Peñailillo, L. (2018). Effects of caffeine on countermovement-jump performance variables in elite male volleyball players. International journal of sports physiology and performance, 13(2), 145-150.
  • Peñailillo, L. E., Escanilla, F. A., Jury, E. R., Castro-Sepulveda, M. A., Deldicque, L., & Zbinden-Foncea, H. (2017). Differences in salivary hormones and perception of exertion in elite women and men volleyball players during tournament. The Journal of Sports Medicine and Physical Fitness, 58(11), 1688-1694.
  • Cancino-Ramírez, J., Soto-Sánchez, J., Zbinden-Foncea, H., Moreno González, M., Leyton-Dinamarca, B., & González-Rojas, L. (2018). Cardiorespiratory fitness and fat oxidation during exercise as protective factors for insulin resistance in sedentary women with overweight or obesity.
  • Rada, I., Deldicque, L., Francaux, M., & Zbinden-Foncea, H. (2018). Toll like receptor expression induced by exercise in obesity and metabolic syndrome: A systematic review.
  • Peñailillo, L., Aedo, C., Cartagena, M., Contreras, A., Reyes, A., Ramirez-Campillo, R., … & Zbinden-Foncea, H. (2020). Effects of eccentric cycling performed at long vs. short muscle lengths on heart rate, rate perceived effort, and muscle damage markers.
  • Castro-Sepulveda, M., Cancino, J., Fernández-Verdejo, R., Pérez-Luco, C., Jannas-Vela, S., Ramirez-Campillo, R., … & Zbinden-Foncea, H. (2018). Basal mild dehydration increase salivary cortisol after a friendly match in young elite soccer players.
  • Kokaly, M., Peñailillo, L., Villagrán, C., Mackay, K., Jannas, S., Deldicque, L., & Zbinden-Foncea, H. (2018). Changes in cortisol and immunoglobulin a concentrations in referees during a professional football match.
  • Flores-Opazo, M., Trieu, J., Naim, T., Valladares-Ide, D., Zbinden-Foncea, H., & Stapleton, D. (2020). Defective fasting-induced PKA activation impairs adipose tissue glycogen degradation in obese Zucker rats.
  • Pérez-Luco, C., Díaz-Castro, F., Jorquera, C., Troncoso, R., Zbinden-Foncea, H., Johannsen, N. M., & Castro-Sepulveda, M. (2019). Fluid restriction decreases solid food consumption post-exercise.
  • González-Bartholin, R., Mackay, K., Valladares, D., Zbinden-Foncea, H., Nosaka, K., & Peñailillo, L. (2019). Changes in oxidative stress, inflammation and muscle damage markers following eccentric versus concentric cycling in older adults.
  • Mackay, K., González, C., Zbinden-Foncea, H., & Peñailillo, L. (2019). Effects of oral contraceptive use on female sexual salivary hormones and indirect markers of muscle damage following eccentric cycling in women.
  • Valladares-Ide, D., Peñailillo, L., Collao, N., Marambio, H., Deldicque, L., & Zbinden-Foncea, H. (2019). Activation of protein synthesis, regeneration, and MAPK signaling pathways following repeated bouts of eccentric cycling.
  • Castro-Sepulveda, M., Cancino, J., Jannas-Vela, S., Jesam, F., Lobos, C., Del Coso, J., & Zbinden-Foncea, H. (2020). Role of basal hormones on sweat rate and sweat Na+ loss in elite women soccer players.
  • Collao, N., Rada, I., Francaux, M., Deldicque, L., & Zbinden-Foncea, H. (2020). Anti-Inflammatory Effect of Exercise Mediated by Toll-Like Receptor Regulation in Innate Immune Cells–A Review.
  • Jannas-Vela, S., Langer, H. T., Marambio, H., Baar, K., & Zbinden-Foncea, H. (2020). Effect of a 12-week endurance training program on force transfer and membrane integrity proteins in lean, obese, and type 2 diabetic subjects.
  • Monje, C., Rada, I., Castro-Sepulveda, M., Peñailillo, L., Deldicque, L., & Zbinden-Foncea, H. (2020). Effects of a high intensity interval session on mucosal immune function and salivary hormones in male and female endurance athletes.
  • Monje, C., Jannas-Vela, S., Baar, K., & Zbinden-Foncea, H. (2020). Case report of an exercise training and nutritional intervention plan in a patient with A350P mutation in DES gene.
  • García-Berger, D., Mackay, K., Monsalves-Alvarez, M., Jorquera, C., Ramirez-Campillo, R., Zbinden-Foncea, H., & Castro-Sepulveda, M. (2020). Effects of skim milk and isotonic drink consumption before exercise on fluid homeostasis and time-trial performance in cyclists.
  • Castro-Sepulveda, M., Jannas-Vela, S., Fernández-Verdejo, R., Ávalos-Allele, D., Tapia, G., Villagrán, C., … & Zbinden-Foncea, H. (2020). Relative lipid oxidation associates directly with mitochondrial fusion phenotype and mitochondria-sarcoplasmic reticulum interactions in human skeletal muscle.
  • Castro-Sepulveda, M., Cancino, J., Jannas-Vela, S., Jesam, F., Lobos, C., Del Coso, J., & Zbinden-Foncea, H. (2020). Role of basal hormones on sweat rate and sweat Na+ loss in elite women soccer players.
  • Valero-Breton, M., Warnier, G., Castro-Sepulveda, M., Deldicque, L., & Zbinden-Foncea, H. (2020). Acute and chronic effects of high frequency electric pulse stimulation on the Akt/mTOR pathway in human primary myotubes.
  • Núñez Lisboa, M., Peñailillo, L. E., Cancino, J., Zbinden-Foncea, H., & Dewolf, A. H. (2021). Influence of sports background on the bouncing mechanism of running.
  • Castro‐Sepulveda, M., Morio, B., Tuñón‐Suárez, M., Jannas‐Vela, S., Díaz‐Castro, F., Rieusset, J., & Zbinden‐Foncea, H. (2021). The fasting‐feeding metabolic transition regulates mitochondrial dynamics.
  • Fuentes, J., Brunser, O., Atala, E., Herranz, J., de Camargo, A. C., Zbinden-Foncea, H., & Speisky, H. (2022). Protection against indomethacin-induced loss of intestinal epithelial barrier function by a quercetin oxidation metabolite present in onion peel: In vitro and in vivo studies.
  • Zbinden-Foncea, H., Castro-Sepulveda, M., Fuentes, J., & Speisky, H. (2022). Effect of Epicatechin on Skeletal Muscle.
  • Jannas-Vela, S., Bustamante, A., Zbinden-Foncea, H., & Peñailillo, L. (2022). Plasma α-Actin as an Early Marker of Muscle Damage After Repeated Bouts of Eccentric Cycling.
  • Mauricio Castro-Sepulveda, Geman Tapia, Mauro Tuñon-Suarez, Alejandra Diaz, Hugo Marambio, Mayalen Valero-Breton, Rodrigo Fernandez-Verdejo, Hermann Zbinden-Foncea. (2022) Severe COVID-19 correlates with lower mitochondrial cristae density in PBMCs and greater sitting time in humans.
  • Mitochondria-SR interaction and mitochondrial fusion/fission in the regulation of skeletal muscle metabolism. Castro-Sepulveda M, Fernández-Verdejo R, Zbinden-Foncea H, Rieusset J. Metabolism. 2023 Jul;144:155578.